Sino-orbital aspergillosis in a diabetic patient.

Sino-orbital and cerebral aspergillosis: cure with medical therapy.

A patient with sino-orbital and cerebral aspergillosis was successfully treated medically without surgical debridement. Anti-fungal agents, including amphotericin B and flucytosine were given over a fifteen month period with improvement in symptoms, resolution of cerebral abscesses by CT scan, and disappearance of serum precipitins to Aspergillus fumigatus. Success was attributed to the long du...

De novo STAT3 Mutation in a Patient with Fatal, Treatment-Refractory Sino-orbital Aspergillosis

Localised invasive sino-orbital aspergillosis: characteristic features.

BACKGROUND/AIM To describe the characteristic constellation of historical, clinical, radiographic, and histopathological findings of localised invasive sino-orbital aspergillosis based on the authors' recent experience of four consecutive cases presenting over a 6 month period. Treatment and outcome are reviewed. METHODS A case series of four patients with review of the English language liter...

Use of MSCs to Modulate Immune Suppression and Immune Reconstruction in a Patient with Aplastic Anemia Complicated by Invasive Sino-Orbital Aspergillosis

Cultured human bone marrow mesenchymal cells (MSCs) have immunomodulatory and tissue regenerative properties. This report summarizes the result of post-transplant treatment with MSCs of a 26-year-old patient with aplastic anemia complicated by invasive sino-orbital aspergillosis. The patient was treated with MSCs to benefit from the dual effects of MSCs in immune reconstitution: suppression aga...

Use of Mesenchymal Cells to Modulate Immune Suppression and Immune Reconstruction in a Patient with Aplastic Anemia Complicated by Invasive Sino-Orbital Aspergillosis

Cultured human bone marrow mesenchymal cells (MSCs) have immunomodulatory and tissue regenerative properties. This report summarizes the result of post-transplant treatment with MSCs of a 26-year-old patient with aplastic anemia complicated by invasive sino-orbital aspergillosis. The patient was treated with MSCs to benefit from the dual effects of MSCs in immune reconstitution: suppression aga...